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Published on: August 14, 2013
慢速输液间歇养与早产婴儿重力养的比较:一项随机对照试验
Funda Yavanoglu Atay1, Ozlem Bozkurt2, Suzan Sahin3
1Department of Pediatrics, Division of Neonatology, Umraniye Training and Research Hospital, 34764 Istanbul, Türkiye.
慢速输液养 (SIF) 可能是早产婴儿食不耐受风险的更好的选择. 与间歇性胆囊养 (IBF) 相比,这种方法减少了胃残留物和非口服状态.
科学领域:
- 新生儿科学 新生儿科学
- 儿科胃肠病学 儿科胃肠病学
- 婴儿营养 婴儿营养
背景情况:
- 确保早产婴儿的适当生长取决于及时过渡到全肠养.
- 食不耐受是早产婴儿的常见并发症,可能会阻碍营养支持和生长.
研究的目的:
- 为了比较缓慢输液养 (SIF) 与间歇性玻尿酸养 (IBF) 的有效性,以促进早产婴儿过渡到全肠养.
- 评估这些养方法对食不耐受和相关结果的影响.
主要方法:
- 一项前性,随机对照性研究,涉及早产婴儿 (妊娠年龄24 + 0/7至31 + 6/7周).
- 婴儿被随机分配到SIF (每3小时1小时的输液) 或IBF (基于重力通过注射器,10-30分钟).
- 主要结局包括完整肠道养的时间和食不耐受的发生率.
主要成果:
- 在SIF和IBF组之间实现完全肠道养的时间没有显著差异 (p = 0.20).
- 在SIF组,胃残留体积超过50%的情况显著减少 (p = 0.01).
- 在SIF组中的婴儿经历了非口服 (NPO) 状态的持续时间明显较短 (p = 0.03).
结论:
- 慢速输液养 (SIF) 是适合早产婴儿体验或患有食不耐受症的高风险的替代方案.
- 在管理胃残留物和减少口服零期时,SIF可能会带来优势.
- 这种养策略支持脆弱的早产人口的营养目标.
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