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非常低出生体重成人的运动能力:系统性审查和元分析
Grace Poole1, Christopher Harris1, Anne Greenough2
1Neonatal Intensive Care Centre, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.
Children (Basel, Switzerland)
|August 26, 2023
概括
与出生时体重非常低 (VLBW) 的成年人相比,与出生时体重非常低的人相比,有氧运动能力降低. 这一发现突出了对VLBW幸存者的潜在的长期心血管健康影响.
科学领域:
- 心脏病学 心脏病学
- 儿科 儿科 儿科
- 运动生理学 运动生理学
背景情况:
- 非常低出生体重 (VLBW) 与增加成人心血管疾病发病率和死亡率有关.
- 以最大氧气消耗 (VO2max) 表示的有氧健身是心肺健康的关键指标和心血管死亡率预测指标.
研究的目的:
- 研究出生体重对成年人有氧运动能力和体力活动水平的影响.
- 为了比较在VLBW出生的人的运动能力和体育活动,而不是出生后的对照.
主要方法:
- 在六个数据库 (MEDLINE,OVID,EMBASE,CINAHL,CENTRAL,Google Scholar) 进行系统的文献搜索.
- 纳入研究报告的运动能力 (VO2最大,VO2峰值) 和体力活动在VLBW成年人 (≥18岁) 与预产期对照相比.
- 在符合条件的研究中使用随机效应模型进行元分析.
主要成果:
- 对10项研究的元分析 (来自15篇相关文章) 显示,VLBW成年人的VO2max显著降低,与预产期对照人群相比 (-3.35mL/kg/min).
- 曾经患有支气管肺功能障碍的VLBW成年人显示VO2max降低甚至更大 (-6.08毫升/千克/分钟).
- 九项研究中有五项报告说,在VLBW个体中,自我报告的体力活动水平有所降低.
结论:
- 在VLBW中出生的成年人表现出相对于按期出生的同龄人而言,最大有氧运动能力下降.
- 在VLBW幸存者的有氧健身能力下降可能会导致他们晚年患心血管疾病的风险增加.
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