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全球批准的药物的重新利用,以潜在地抑制人类碳酸无水酶I:一项计算研究

Nannan Zheng1, Wanyun Jiang1, Puyu Zhang1

  • 1Department of Biological Science and Engineering, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China.

International journal of molecular sciences
|August 26, 2023
PubMed
概括

三种化合物,包括环亚胺,对人类碳酸无水酶 (hCA) 具有强烈的结合亲和力,表明它们作为治疗疾病的有效hCA抑制剂的潜力.

关键词:
药物重用是为了改变药物的用途.金属酶 - - 金属酶.分子模拟分子模拟受体-连接体相互作用.

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