非热等离子体在医学中的应用 - - 专注于反应性物种参与
Julia Moszczyńska1, Katarzyna Roszek2, Marek Wiśniewski1
1Department of Materials Chemistry, Adsorption and Catalysis, Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Gagarina 7, 87-100 Toruń, Poland.
International journal of molecular sciences
|August 26, 2023
概括
非热等离子体 (NTP) 提供了多方面的医疗应用,包括微生物无活化和细胞调节用于治疗. 对NTP进行进一步的研究.
科学领域:
- 医学 医学 医学 医学 医学
- 物理 物理学 物理
- 化学 化学 化学
背景情况:
- 非热等离子体 (NTP) 是一个正在发展的跨学科领域,对医学应用越来越感兴趣.
- 自19世纪以来,人们就已经知道了等离子体现象,但最近的注意力集中在它的治疗潜力上.
研究的目的:
- 审查在人类/动物组织和细菌中NTP应用中涉及的潜在化学过程和反应性物种.
- 描述医学表面的等离子体介导修改,如手术仪器和植入物.
- 突出基于NTP的新型治疗方法的机会.
主要方法:
- 对基于NTP的体外和体内研究现有知识的审查.
- 在NTP中解释化学过程和反应物种.
- 通过等离子介导的表面修饰的描述.
主要成果:
- NTP表现出三个关键效应:微生物失活,刺激细胞增殖/血管生成 (低强度),以及细胞失活/死亡诱导 (高强度).
- NTP有助于杀菌,并通过细菌不活化间接支持伤口愈合.
- 等离子体可以修改医疗表面以提高生物相容性或功能.
结论:
- 对NTP机制的全面理解对于推进基于血的医学至关重要.
- 在新型治疗策略和医疗器械开发方面,NTP具有显著的潜力.
- 需要进一步的研究才能充分利用NTP在临床环境中的功能.
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