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基于的癌症治疗剂:当前的应用和未来的方向
Nguyễn Thị Thanh Nhàn1, Tohru Yamada2,3, Kaori H Yamada1,4
1Department of Pharmacology & Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL 60612, USA.
基于的癌症治疗显示出有望针对性交付和个性化医学的承诺. 虽然抗癌 (ACP) 在试验中有效,但很少有FDA批准用于固体瘤,这凸显了进一步发展的需要.
科学领域:
- 在瘤学瘤学.
- 生物技术是生物技术.
- 药物发现 药物发现 药物发现
背景情况:
- 基于的策略为癌症诊断和治疗提供了高特异性和瘤向能力.
- 具有抗癌活性 (ACP) 的生物活性是有利的,因为有针对性的交付,个性化的设计,小尺寸和简单的生产.
研究的目的:
- 审查癌症治疗的基策略的最新进展和未来前景.
- 详细概述目前的方法,设计策略,施用途径和基于的癌症治疗技术进步.
主要方法:
- 使用PubMed (2023年6月之前) 和ClinicalTrials.gov进行文献搜索,查找相关文章和临床试验信息.
- 专注于类药物联合体 (PDC),诊断应用,图像引导手术和通过类疫苗进行免疫调节.
主要成果:
- 基于的策略在临床前和临床环境中显示出显著的潜力,特别是针对性输送和免疫调节.
- 类药物合物 (PDC) 和类疫苗显示出有前途,在临床试验中进行了广泛的测试.
结论:
- 尽管有针对性交付和个性化设计等优势,但FDA批准的固体癌症类药物的数量仍然有限.
- 需要进一步的研究和开发来克服局限性,并充分实现基于的癌症疗法的潜力.
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