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Updated: Jul 31, 2026

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain
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Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain

Published on: November 18, 2013

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粉样蛋白前体蛋白 (APP) 通过几个信号通路调节人类神经干细胞的质生成和神经生成

Raquel Coronel1,2, Adela Bernabeu-Zornoza1, Charlotte Palmer1

  • 1Unidad de Regeneración Neural, Unidad Funcional de Investigación de Enfermedades Crónicas, Instituto de Salud Carlos III, Majadahonda, 28220 Madrid, Spain.

International journal of molecular sciences
|August 26, 2023
PubMed
概括

粉样蛋白前体蛋白 (APP) 影响人类神经干细胞的分化. 过度表达APP会影响关键信号通路中的基因,为阿尔茨海默氏症 (AD) 病变产生提供新的见解.

关键词:
有关RNA测序的RNA测序粉样蛋白前体蛋白质是粉样蛋白的前体.质体的产生是质体的产生.神经干细胞的神经干细胞神经发生神经发生.信号通道是指信号通道.

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Methods of Nuclear Reprogramming01:24

Methods of Nuclear Reprogramming

Nuclear reprogramming is a process of transforming one cell type into an unrelated cell type by epigenetic changes that alter the cell’s original gene expression pattern. Such epigenetic changes force cells to express a different set of genes, which play a significant role in inducing transformation into other cell types. Nuclear reprogramming offers applications in reproductive cloning for livestock propagation and regenerative medicine — developing patient-specific cells for injury repair.