隔膜功能障碍和ICU获得的软弱在感染性休克患者与或没有机械通风:一个试点前性观察性研究
Yuta Takahashi1,2, Tomoyuki Morisawa3, Hiroshi Okamoto4
1Department of Rehabilitation Medicine, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan.
Journal of clinical medicine
|August 26, 2023
概括
败血症患者经常出现隔膜功能障碍和ICU获得的虚弱,无论机械通风如何. 隔膜功能障碍在通风和非通风的败血症休克患者中发生的频率高于ICU获得的弱点.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 神经学 神经学
背景情况:
- 败血症是膜功能障碍和重症监护室获得的虚弱 (ICU-AW) 的已知危险因素.
- 机械通风 (MV) 对性休克患者这些情况的具体影响需要进一步调查.
研究的目的:
- 为了比较隔膜功能障碍和ICU-AW在有和没有机械通风的败血症休克患者的发病率.
- 探索这些疾病与临床结果之间的关联.
主要方法:
- 在一个单一中心进行前性观察研究.
- 包括连续感染性休克患者入住ICU.
- 评估隔膜厚度通过超声波和肢体肌肉强度手动ICU入院后.
主要成果:
- 隔膜功能障碍在MV (72.7%) 和非MV (76.9%) 组中都非常普遍.
- 与非MV组 (23.1%) 相比,MV组的ICU-AW发生率更高 (54.5%).
- 隔膜功能障碍与临床结果之间没有发现关联;然而,MV组的ICU-AW与更长的ICU和住院时间相关.
结论:
- 隔膜功能障碍在败血症休克患者中很常见,无论机械通风如何.
- 在ICU获得的软弱也很普遍,特别是在机械通风患者.
- 需要进一步的研究来澄清隔膜功能障碍与败血症临床结果之间的关系.
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