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用OCT血管学评估单克隆性乳腺病患者视网膜血液流动情况

Cecilia Czakó¹, Dóra Gerencsér¹, Kitti Kormányos¹

¹Department of Ophthalmology, Semmelweis University, 1085 Budapest, Hungary.

Journal of clinical medicine

|August 26, 2023

概括

光学连贯断层扫描血管造影 (OCTA) 显示,单克隆性淋巴病 (MG) 患者的表面视网膜毛细血管密度降低. 这一发现表明血液循环受损和潜在的组织输血不足,突出显示了OCTA.

科学领域:

眼科医生眼科眼科
血液学血液学血液学
医疗成像医学成像

背景情况:

单克隆性甘美病 (MG) 涉及异常蛋白质的产生,并可能导致超粘性综合征.
视网膜微循环可能会受到MG患者血粘度增加的影响.

研究的目的:

为了评估MG患者的视网膜循环,使用光学连贯性断层扫描血管学 (OCTA).
为了比较MG患者和健康对照之间的OCTA参数.

主要方法:

用Optovue AngioVue系统对27名MG患者和36名对照进行了OCTA.
测量包括表面和深层毛细血管密度 (VD SVP,DVP),叶无血管区 (FAZ) 面积和中央视网膜厚度 (CRT).
用多变量回归分析数据,控制图像质量.

主要成果:

两组之间没有发现显著的年龄差异.
表面视网膜毛细血管密度 (VD SVP) 在MG患者中与对照组相比显著较低 (p <0.05).
在DVP,FAZ区域或CRT中没有发现显著差异.

结论:

在MG患者中减少的VD SVP表明血液流动减慢,毛细血管循环减少.
OCTA可以作为一种敏感的,非侵入性的工具,用于检测和监测MG的早期微循环功能障碍.
这种功能障碍很可能是由于与单克隆性胃病变相关的血液粘度增加.

关键词:

超粘度综合征是一种超粘度综合征.单克隆性牙病变是一种单克隆性牙病变.多发性骨髓瘤是多发性骨髓瘤的一种.光学连贯性断层扫描血管图谱

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