用更少的时间做得更多? 在患有先天性肺部形症的患者中,分片切除术与分片切除术相比
Beatrice Trabalza Marinucci1, Cecilia Menna1, Paolo Scanagatta2
1Thoracic Surgery Sant'Andrea Hospital, La Sapienza University, 00186 Rome, Italy.
Journal of clinical medicine
|August 26, 2023
概括
肺叶切除术对于先天性肺形 (CPM) 比下叶切除更有效,减少症状复发和并发症. 这项研究比较了成人和儿科中CPM的手术方法.
科学领域:
- 胸部外科手术 胸部外科手术
- 儿科手术 儿科手术
- 手术瘤学手术瘤学
背景情况:
- 先天性肺形 (CPM) 是一种罕见的良性病变,有可能导致并发症和恶性转变.
- 对于CPM,甚至在无症状病例中,外科干预通常是必要的.
- 对CPM的最佳外科切除程度在儿科和成人患者中缺乏共识.
研究的目的:
- 确定先天性肺形 (CPM) 的最有效的外科切除策略.
- 确定预防症状复发并最大限度地减少CPM患者并发症的手术方法.
- 为了比较CPMs的分叶切除和分叶切除之间的结果.
主要方法:
- 在四个中心对96名成人和儿科患者进行回顾性分析,这些患者在2010-2020年期间接受了CPM手术.
- 倾向性得分匹配 (2:1) 来比较分叶切除术 (50名患者) 和分叶切除术 (25名患者) 之间的结果.
- 临床,组织病理学,并发症和复发数据的单变量和多变量分析.
主要成果:
- 输卵管切除组的症状复发率明显较低 (4%对24%,p=0.014) 和手术内并发症较少 (p=0.014).
- 后勤回归确定了亚叶叶切除 (p=0.040) 作为复发的危险因素.
- 术内并发症 (p=0.105),术后并发症 (p=0.022) 和相关瘤 (p=0.062) 也与复发有关.
结论:
- 肺叶切除术似乎是对CPM最有效的手术治疗方法.
- 腹腔切除术确保了症状的稳定缓解,并减少了手术前后并发症.
- 这项研究为罕见的CPM的最佳外科治疗提供了宝贵的见解.
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