新的间歇性尿路微孔区域导管显示在清空膀方面提高了性能:一个随机的,受控的交叉研究
Malene Hornbak Landauro1, Lotte Jacobsen1, Fabio Tentor1
1Coloplast A/S, 3050 Humlebæk, Denmark.
Journal of clinical medicine
|August 26, 2023
概括
一种新的微孔区域导管 (MHZC) 在干净间歇性导管 (CIC) 用户中显著减少尿路感染 (UTI). 这种创新的导管设计改善了膀的排空,最大限度地减少了剩余的尿液和导管重新定位的需求.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医疗器械 医疗器械
- 预防传染病 预防传染病
背景情况:
- 尿路感染 (UTI) 是干净间歇性导管治疗 (CIC) 的常见并发症,特别是在膀不完全排空的患者中.
- 剩余的尿液是CIC用户中尿路感染的重要危险因素.
- 传统的眼导管 (CECs) 可能导致膀不完全排空,并增加尿路感染的风险.
研究的目的:
- 为了比较新型微孔区域导管 (MHZC) 与常规眼孔导管 (CEC) 在改善CIC期间膀排空的疗效.
- 评估MHZC对减少流量停止事件和余尿量的影响.
主要方法:
- 一项受控交叉研究,涉及42名成年男性CIC用户.
- 参与者被随机分配在单独的测试访问中使用MHZC或CEC.
- 副主终点是第一个流量停止时的流量停止事件数量和余尿量.
主要成果:
- 与CEC (平均1.09) (p < 0.001) 相比,MHZC的流量停止事件显著减少 (平均0.17).
- 与MHZC (平均5.10毫升) 与CEC (平均39.40毫升) 相比,观察到的尿液残留量明显较少 (p < 0.001).
- 在这项研究中,对任何一种导管类型都没有报告任何不良事件.
结论:
- 对于CIC来说,MHZC提供了比CEC更好的性能,促进了完全的膀排空.
- 改进的MHZC设计导致减少流量停止和余尿,可能降低尿路感染发病率.
- MHZC确保了不间断的尿流,消除了需要导管重新定位的必要性,直到膀空虚完成.
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