探索当前的概念和挑战,以识别和管理早期的COPD
Esperanza Doña1, Rocío Reinoso-Arija2, Laura Carrasco-Hernandez2,3
1Unidad Médico-Quirúrgico de Enfermedades Respiratorias, Hospital Regional Universitario de Málaga, 29010 Málaga, Spain.
Journal of clinical medicine
|August 26, 2023
概括
识别早期慢性阻塞性肺病 (COPD) 是复杂的,没有普遍的定义. 本综述探讨了COPD前和PRISM等新兴概念,以帮助早期诊断和干预.
科学领域:
- 肺部病理学 肺部病理学
- 呼吸系统医学 呼吸系统医学
- 临床医学 临床医学
背景情况:
- 改善健康结果和疾病预后需要早期识别慢性阻塞性肺病 (COPD).
- 早期干预被假设对COPD进展有更大的预后影响.
- 目前对早期COPD的操作定义复杂,缺乏普遍接受.
研究的目的:
- 审查和讨论新出现的概念,以识别早期的慢性肺炎.
- 突出COPD在发病时的定义的重要性和挑战.
- 强调需要对临床试验设计和治疗向进行普遍接受的定义.
主要方法:
- 审查当前文献和GOLD (慢性阻塞性肺病全球倡议) 提出的概念.
- 讨论COPD在年轻人中的COPD,轻度功能障碍,COPD前期和PRISm等概念.
- 对这些概念的临床相关性和普遍采用挑战的分析.
主要成果:
- 已经提出了几种概念,包括COPD前和PRISM,以识别有风险的个人和早期的COPD.
- 这些概念旨在检测有症状的非阻塞性特征或维护比率的患者,其螺旋计受损.
- 尽管有潜力,但这些概念在医学界尚未得到普遍采用.
结论:
- 对早期COPD的普遍接受的定义对于推进研究和临床实践至关重要.
- 识别有风险或处于COPD初期阶段的患者对于有效的治疗策略至关重要.
- 需要进行进一步的研究和达成共识,以建立用于早期COPD检测的标准化方法.
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