上呼吸道特征和形态变化由不同的MADs在OSA成人受试者通过CBCT3D成像评估的上呼吸道特征和形态变化
Nicolò Venza1, Arianna Malara1, Claudio Liguori2
1Department of Systems Medicine, University of Rome "Tor Vergata", Viale Oxford 81, 00133 Rome, Italy.
Journal of clinical medicine
|August 26, 2023
概括
前进装置 (MADs) 通过增加上呼吸道体积,有效治疗阻塞性睡眠呼吸暂停 (OSA). 不同的MAD设计影响治疗的有效性,MAD Forward和TAP在OSA患者中显示出最大的呼吸道扩张.
科学领域:
- 牙科 睡眠医学 睡眠医学
- 呼吸系统医学 呼吸系统医学
- 医疗成像医学成像
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种常见的睡眠障碍,其特征是重复的上呼吸道崩.
- 前进装置 (MAD) 是一种常见的OSA治疗方法,但它们的有效性可能有所不同.
- 了解不同MAD设计引起的形态变化对于优化治疗至关重要.
研究的目的:
- 分析四种不同的下前进装置 (MAD) 设计在治疗阻塞性睡眠呼吸暂停 (OSA) 的有效性.
- 通过使用圆束计算机断层扫描 (CBCT) 来评估由这些MADs诱导的上呼吸道特征的形态变化.
- 为了比较不同MAD设计在气道体积和面积扩大方面的有效性.
主要方法:
- 22名OSA患者在MAD治疗前后接受了多睡眠图 (PSG) 和CBCT扫描.
- 使用了四种定制的,可定位的MAD,患者接受治疗六个月.
- 使用专门的软件分析CBCT扫描,以测量口腔大区和体积变化.
主要成果:
- 在OSA患者中,MAD治疗显著改善了上呼吸道体积的33.76%.
- 在后软 (+32.41%) 和后舌 (+36.96%) 区域观察到显著的扩张比.
- MAD Forward和TAP设计的气道体积增长最大 (+42.77%和+41.63%,分别).
结论:
- MAD疗法是适度至严重的OSA的有效治疗方法,导致上呼吸道体积增加.
- 一个MAD的特定设计可以影响其在改善气道尺寸方面的有效性.
- CBCT成像为MADs诱导的上呼吸道的形态变化提供了宝贵的见解.
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