慢性阻塞性肺部疾病患者的长期临床结果与萨科佩尼亚
Yong Jun Choi1, Taehee Kim1, Hye Jung Park1
1Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Republic of Korea.
Life (Basel, Switzerland)
|August 26, 2023
概括
皮症显著恶化慢性阻塞性肺病 (COPD) 患者的结果,增加急性恶化和死亡率. 早期监测和干预,如炼和营养,对于治疗肉症的慢性肺炎至关重要.
科学领域:
- 肺部医学 肺部医学
- 老年病的医生 老年病的医生
- 肌肉生理学 肌肉生理学
背景情况:
- 标志着肌肉消耗和肌肉衰弱的萨科佩尼亚,在患有慢性阻塞性肺病 (COPD) 的患者中很普遍.
- 萨科佩尼亚对COPD患者的临床影响仍然是一个引人注目的领域.
研究的目的:
- 研究被诊断患有慢性肺炎的患者的萨尔科佩尼亚和临床结果之间的关联.
- 为了确定sarcopenia作为潜在的COPD不良事件的风险因素.
主要方法:
- 从2012年到2018年,对71名COPD患者的电子病历进行了回顾性审查.
- 纵向分析比较COPD患者与非sarcopenia之间的临床结果.
主要成果:
- 与非sarcopenia组相比,sarcopenia组的COPD急性恶化率 (AE COPD) (84.6%对31.0%) 和所有原因死亡率 (30.8%对5.2%) 显着更高.
- 标出了萨科佩尼亚作为AE COPD (危险比率,5.982) 的独立风险因素.
- 肌肉质量指数 (SMMI) 和手握强度显示与疾病严重程度,生活质量 (CAT得分) 和恶化频率有关.
结论:
- 萨科佩尼亚与较差的临床预后,肺炎风险增加以及COPD患者急性恶化需要密集护理的可能性更高有关.
- 建议对COPD患者进行密切监测,以检查皮症的发展.
- 应考虑适当的运动和营养干预措施来管理COPD患者.
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