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进行融合前列腺活检的患者周围抽样的作用

Riccardo Lombardo¹, Giorgia Tema¹, Antonio Nacchia¹

¹Ospedale Sant'Andrea, Sapienza University of Rome, 00185 Rome, Italy.

Life (Basel, Switzerland)

|August 26, 2023

概括

在前列腺活检中取样可能会减少不必要的手术. 然而,这种策略存在错过临床意义上的前列腺癌的风险,需要进一步进行成本效益分析.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
在瘤学瘤学.
放射学放射学是一门学科.

背景情况:

前列腺癌的诊断通常依赖于系统的活检.
周围取样是减少不必要的活检的替代方案.
融合活检将MRI成像与超声指导相结合,用于有针对性的采样.

研究的目的:

为了评估临床采样在避免进行系统活检的有效性,为患者进行融合活检.
为了比较不同活检策略的癌症检测率.

主要方法:

一项针对262名接受跨直肠MRI-跨直肠融合活检的患者的前性队列研究.
患者接受了系统活检 (SB),向活检 (TB) 和周活检 (PB) 在损伤的10毫米范围内.
分析了每个策略的癌症检测率.

主要成果:

总体癌症检测率为43.5%,临床显著的前列腺癌 (csPCa) 检测率为35%.
目标+周目标策略检测到32.8%的癌症和29%的csPCa (等级组>2).
这种方法错过了7%的csPCa病例,但避免了3%的非显著前列腺癌 (nsPCa) 诊断.

结论:

周围抽样与有针对性的活检相结合,可以减少不必要的前列腺活检.
这种策略存在错过临床意义上的前列腺癌的风险.
需要进一步的研究来评估各种活检策略的成本效益.

关键词:

周边抽样采样周边抽样前列腺活检活检前列腺活检有针对性的活检.

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