评估和预测对甲索特雷克萨特的坚持,使用三个自我报告问卷在患有类风湿性关节炎的患者
Jelena Ceranic1,2, Darija Kisic Tepavcevic2, Milan Petronijevic1,3
1Department of Rheumatology and Clinical Immunology, Military Medical Academy, 11040 Belgrade, Serbia.
Medicina (Kaunas, Lithuania)
|August 26, 2023
概括
在类风湿性关节炎患者中,甲状腺素 (MTX) 不坚持是常见的. 同时的类固醇治疗是MTX坚持的关键预测因素,改善治疗结果.
科学领域:
- 类风湿病学 类风湿病学
- 临床药房 临床药房
- 患者坚持的研究研究.
背景情况:
- 甲基 (MTX) 对于控制类风湿性关节炎 (RA) 活动和长期功能至关重要.
- 患者对MTX的坚持对于治疗疗效至关重要.
- 不遵守MTX仍然是RA管理中的一个重大挑战.
研究的目的:
- 评估类风湿性关节炎患者的甲索特雷克萨特坚持率.
- 为了确定与甲状腺素不依附相关的特定风险因素.
主要方法:
- 一项涉及111名RA患者的横截面研究.
- 使用了三个依从性自我评估问卷:CQR19,MARS-5和VAS.
- 收集的人口,疾病,治疗和心理数据 (HADS).
主要成果:
- 根据问卷的依赖率有所不同: 48.6% (CQR19), 70.3% (MARS-5), 82.9% (VAS).
- 在所有三种遵守措施之间观察到正相关性.
- 城市居住,女性性别和MTX剂量预测了坚持;并发症,抑郁症和年龄较大预测了不坚持.
- 同时使用类固醇是所有问卷和多变量分析中显著的积极预测因素.
结论:
- 很大一部分类风湿性关节炎患者表现出不坚持甲索特酸的情况.
- 同时的类固醇治疗是MTX坚持的独立积极预测因素.
- 了解坚持因素可以为RA管理提供有针对性的干预措施.
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