波兰患有帕金森病的患者群体中的冲动控制障碍
Mateusz Toś1, Anna Grażyńska2, Sofija Antoniuk3
1Department of Neurology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-055 Katowice, Poland.
Medicina (Kaunas, Lithuania)
|August 26, 2023
概括
冲动控制障碍 (ICD) 影响超过四分之一的波兰帕金森病 (PD) 患者,通常与多巴胺激动剂治疗有关. 早期检测至关重要,因为常规查错过了许多病例.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 帕金森病 (PD) 呈现出运动和非运动症状,包括冲动控制障碍 (ICD).
- 强迫性疾病包括诸如强迫性博,过度性欲,暴饮暴食和购物等疾病.
- 多巴胺治疗,特别是多巴胺激动剂 (DA),是PD患者中ICD的已知危险因素.
研究的目的:
- 在帕金森病的背景下,对波兰患有ICD的患者进行分析.
- 为了确定波兰PD患者中ICD的频率.
- 在这个人群中确定ICD的风险因素.
主要方法:
- 这是一项前性研究,涉及135名特异性PD患者.
- 使用帕金森病冲动-强迫性障碍问卷 (QUIP) 评估ICD.
- 用MDS-UPDRS第三部分和Hoehn-Yahr分期评估运动症状;收集临床和药物数据.
主要成果:
- 在27.41%的波兰PD患者中发现了ICD.
- 与非使用者 (54.07%) 相比,使用多巴胺激动剂 (DA) 的患者中观察到更高的ICD患病率 (83.78%).
- 风险因素包括较长的疾病持续时间,运动并发症,睡眠障碍和DA/L-dopa使用;只有13.51%的ICD病例通过病史被检测出来.
结论:
- 在波兰PD患者中,ICD很常见,与多巴胺类疗法有显著的关联.
- 疾病持续时间较长,运动并发症,睡眠障碍和特定药物是关键的危险因素.
- 低检测率凸显了医生提高医生的意识和针对性查需要在PD患者中进行ICD.
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