卵巢癌患者的心血管死亡率:使用SEER数据库分析患者特征
Ismail Abdulrahman Al-Badawi1, Osama Alomar1, Saud Owaimer Alsehaimi1
1Department of Obstetrics and Gynecology, King Faisal Specialist Hospital and Research Center, Riyadh 11564, Saudi Arabia.
Medicina (Kaunas, Lithuania)
|August 26, 2023
概括
心血管疾病 (CVD) 是卵巢癌患者的一个重大问题. 晚期,老年和非白人种族增加了心血管疾病的风险,突出了提高生存率的有针对性的干预措施的需要.
科学领域:
- 在瘤学瘤学.
- 心脏病学 心脏病学
- 流行病学 流行病学
背景情况:
- 心血管疾病 (CVD) 显著导致卵巢癌患者的死亡率.
- 对于这种人群中患心血管疾病的患者特异性风险因素的了解有限.
研究的目的:
- 在被诊断为卵巢癌的个体中,确定与心血管死亡相关的患者特征.
- 为提高生存率提供有针对性的干预措施的信息.
主要方法:
- 使用SEER数据库 (2000-2019) 进行的回顾性队列研究.
- 对原发性卵巢癌病例的分析.
- 多变量后勤回归用于识别心血管死亡的风险因素.
主要成果:
- 差异化癌症和远程转移与较高的心血管疾病死亡率相关.
- 60岁以上的年龄,晚年诊断年龄,非白人种族,双边疾病和远程阶段是显著的危险因素.
- 31-60岁的患者与老年患者相比,心血管疾病死亡风险较低.
结论:
- 心血管死亡率是卵巢癌管理中的一个关键问题.
- 识别高风险患者 (例如,晚期,并发症) 可以实现针对性心血管健康干预.
- 改善卵巢癌患者的心血管健康可能会提高整体存活率.
更多相关视频
09:08Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
Published on: January 12, 2020
6.8K
06:46Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
302
相关概念视频
Cancer Survival Analysis
383
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
383
Comparing the Survival Analysis of Two or More Groups
222
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
222
Kaplan-Meier Approach
179
The Kaplan-Meier estimator is a non-parametric method used to estimate the survival function from time-to-event data. In medical research, it is frequently employed to measure the proportion of patients surviving for a certain period after treatment. This estimator is fundamental in analyzing time-to-event data, making it indispensable in clinical trials, epidemiological studies, and reliability engineering. By estimating survival probabilities, researchers can evaluate treatment effectiveness,...
179
