在斋月期间肠道微生物组的改变为斋月禁食提供了新的视角:试点研究
YoungJae Jo1, GyuDae Lee1, Sajjad Ahmad1
1Department of Applied Biosciences, Kyungpook National University, Daegu 41566, Republic of Korea.
Microorganisms
|August 26, 2023
概括
斋月禁食可能不会像间歇性禁食一样有益于肠道健康. 研究表明,斋月期间有益细菌和短链脂肪酸 (SCFA) 减少,这表明对强壮的肠道微生物群的营养摄入不足.
科学领域:
- 微生物学 微生物学
- 营养科学 营养科学
- 胃肠病学 胃肠病学
背景情况:
- 间歇性禁食 (IF) 与减肥和改善胰岛素抵抗等健康益处有关.
- 斋月禁食经常被误认为IF,尽管饮食模式的关键差异.
- 了解斋月禁食对肠道微生物群的影响至关重要.
研究的目的:
- 调查斋月禁食是否与IF具有类似的肠道微生物组益处.
- 为了监测在斋月期间和之后肠道微生物群组成和功能的变化.
主要方法:
- 在斋月期间4周和斋月后8周研究了20名穆斯林个人.
- 分析了便微生物组合的组成.
- 使用液体染色学质谱法量化的短链脂肪酸 (SCFA).
主要成果:
- 在斋月期间观察到SCFA和有益细菌的减少.
- 在斋月之后的时期,发现微生物多样性增加.
- 鉴定了功能基因的显著差异,以及 *Lactobacillus* 和 SCFA 之间的相关性.
结论:
- 斋月禁食可能不会支持强大的肠道微生物群,因为潜在的营养不足.
- 斋月期间的饮食模式可能与IF相差足以改变肠道微生物群.
- 需要进一步的研究来阐明长期影响和机制.
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