益生菌对职业健康中的抑郁障碍的影响和选择:范围审查
José Antonio Picó-Monllor1, Elena Sala-Segura1, Romina Alin Tobares2
1Department of Pharmacology, Pediatrics and Organic Chemistry, Faculty of Pharmacy, Miguel Hernández University (UMH), 03202 Elche, Spain.
Nutrients
|August 26, 2023
概括
益生菌显示出治疗抑郁症的潜力,特别是在劳动人口中. 特定的菌株,如Bifidobacterium和Lactobacillus,可能在治疗中提供辅助益处.
科学领域:
- 职业健康 职业健康 职业健康
- 微生物学 微生物学
- 精神病学是一个精神病学.
背景情况:
- 抑郁症严重影响工作场所的生产力,并带来大量的经济和医疗费用.
- 益生菌,定义为活的有益微生物,越来越多地研究其促进健康的特性.
- 新兴研究表明,益生菌在治疗抑郁症方面可能发挥作用,尽管研究结果各不相同.
研究的目的:
- 系统地评估益生菌在预防或治疗抑郁症疾病中的有效性和安全性.
- 在职业健康的背景下,确定有益于心理健康的特定益生菌菌株和组合.
主要方法:
- 在主要数据库 (MEDLINE,EMBASE,Cochrane,Scopus,Web of Science) 中进行了全面的文献搜索.
- 关键词包括"职业健康"",益生菌"",抑郁症"和"抑郁症",仅限于人类临床试验.
- 根据预定义的纳入和排除标准,选择了18项研究进行批判性分析.
主要成果:
- 对18项临床试验的分析表明,某些益生菌组合可能是有效的.
- 来自*Bifidobacterium*和*Lactobacillus*属的菌株经常被确定为可能有益的菌株.
- 这些发现表明,这些益生菌在治疗抑郁症中可能起到辅助作用.
结论:
- *Bifidobacterium*和*Lactobacillus*菌株的组合显示出作为抑郁症障碍的辅助治疗的希望.
- 这种益生菌方法可能特别适用于那些经历了与抑郁症有关的职业健康挑战的劳动人口.
- 需要进一步的研究来证实疗效和优化治疗方案.
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