结合双极射频和非交叉链接的氨酸美苏疗法协议,以改善皮肤外观和表皮屏障功能:试点研究
Anna Płatkowska1, Szymon Korzekwa1, Bartłomiej Łukasik2
1Anclara Health & Aesthetics, 02624 Warsaw, Poland.
Pharmaceuticals (Basel, Switzerland)
|August 26, 2023
概括
这项研究发现,将双极射频与氨酸 (HA) 中位疗法结合起来,比单独使用射频更能显著改善皮肤水分,坚硬性和肌肤色调. 协同效应增强了表皮平衡和屏障功能,以改善面部外观.
科学领域:
- 皮肤病学 皮肤病学
- 审美医学是一种美学医学.
- 化品科学 化品科学
背景情况:
- 与年龄相关的皮肤变化,如干燥和松影响外观.
- 表皮水分,色素,厚度和细胞更新是关键因素.
- 非交叉链接的氨酸 (HA) 中和疗法是一种潜在的治疗方法.
研究的目的:
- 评估双极射频 (RF) 加上HA介质疗法的协同效应.
- 为了在皮肤外观上比较这种组合治疗与单独的射频.
- 评估对表皮功能标记物的影响.
主要方法:
- 对干燥松皮肤的女性 (25-65岁) 进行前性,分脸试点研究.
- 双极性RF应用于脸部的两侧;一侧的HA介质疗法.
- 在28天后评估过表皮水损失 (TEWL),水合,黑色素,红斑,表皮厚度和密度.
主要成果:
- 与单独使用射频相比,联合射频+HA显著改善了皮肤水分 (+23.1% vs +1.0%) 和降低了TEWL (-5.8% vs +3.9%).
- 在这种组合中,黑色素 (-7.5% vs -1.5%) 和红斑 (-7.2% vs +3.0%) 的改善更大.
- 超声波显示,结合治疗时表皮厚度 (12.0%对5.6%) 和密度 (57.7%对7.1%) 增加.
结论:
- 双极性射频和HA介质疗法方案的结合提供了在皮肤水分,性和色调方面的卓越改进.
- 观察到对表皮平衡和屏障功能的协同效应.
- 这两种治疗都被很好地容忍,增强了面部外观.
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