相关实验视频

Updated: Jul 18, 2025

Author Spotlight: Innovative Microneedle-Based Strategies for Enhanced Exosome Delivery and Stability
07:41

Author Spotlight: Innovative Microneedle-Based Strategies for Enhanced Exosome Delivery and Stability

Published on: July 12, 2024

2.3K

通过皮肤输送glimepiride:使用纳米细胞嵌入微针的新方法

Sadia Pervez1, Fazli Nasir1, Talaya Hidayatullah1

  • 1Department of Pharmacy, University of Peshawar, Peshawar 25000, Pakistan.

Pharmaceutics
|August 26, 2023
PubMed
概括

这项研究开发了装有格莱梅皮里德 (GM) 纳米细胞的微针,用于通过皮肤递送药物. 与口服相比,这种新的方法显著提高了转基因溶解度和生物可用性,提供了更安全,更有效的治疗选择.

关键词:
BCS II类药物 BCS II类药物 BCS II类药物 BCS II类药物在Soluplus®中使用Soluplus®.甲基化物 甲基化物微针是一种微针.它们是纳米微粒.颗粒大小分布 粒子大小分布药物动力学参数 药物动力学参数通过皮肤传递药物.

更多相关视频

Polymeric Microneedle Array Fabrication by Photolithography08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

12.2K
Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.4K

相关概念视频

Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
380
Oral Hypoglycemic Agents: Glinides01:06

Oral Hypoglycemic Agents: Glinides

Repaglinide (Prandin) and Nateglinide (Starlix), known as glinides, are oral insulin secretagogues that stimulate insulin release from pancreatic β cells by closing the ATP-sensitive potassium channels (KATP channel). Repaglinide controls insulin release from pancreatic β cells by managing potassium efflux. It shares two binding sites with sulfonylureas and also has a unique site, indicating overlapping mechanisms of action. With a rapid onset and a 4-7 hour duration, it effectively...
184
Drug Delivery: Enteral Route01:18

Drug Delivery: Enteral Route

The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
503
Drug Delivery: Overview01:16

Drug Delivery: Overview

The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
321
Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
612