在初级接种疫苗后,COVID-19在养老院爆发的影响
Elba Mauriz1,2, José P Fernández-Vázquez3, Cristina Díez-Flecha4
1ALINS, Food Nutrition and Safety Group, ICTAL Universidad de León, 24007 Leon, Spain.
Vaccines
|August 26, 2023
概括
即使在接种疫苗后,养老院的老年居民仍然面临COVID-19的高风险. 接种疫苗和症状出现之间的时间显著影响住院和死亡率,强调需要继续采取预防措施.
科学领域:
- 老年学是一门学科.
- 传染病流行病学 传染病流行病学
- 公共卫生 公共卫生
背景情况:
- 养老院居民由于免疫衰老和并发性疾病,非常容易感染COVID-19.
- 从长期护理机构的员工和访客中传播的风险较高.
- 这项研究检查了在初始接种疫苗后的养老院COVID-19结果.
研究的目的:
- 描述第一剂疫苗接种后在老年护理机构中COVID-19爆发的结果.
- 确定与住院和死亡率相关的变量.
- 评估疫苗接种时间对严重结果的影响.
主要方法:
- 在一个单一的长期护理机构进行了回顾性观察性研究.
- 后勤回归分析以确定影响住院和死亡的因素.
- 调整的赔率比率 (aOR) 和95%的置信区间 (CI) 的计算.
主要成果:
- 尽管初步接种了疫苗,但仍发生了COVID-19疫情,居民 (75.0%) 和工作人员 (56.3%) 的阳性率很高.
- 95.58%的居民出现症状,34.9%住院,25.8%死亡.
- 接种疫苗和症状出现之间的每一天,住院风险降低了43% (aOR=0.57),死亡风险降低了26% (aOR=0.74).
结论:
- 养老院面临着严重的SARS-CoV-2传播和严重性风险.
- 虽然疫苗接种降低了住院和死亡风险,但严格的预防仍然至关重要.
- 接种疫苗的时间是缓解脆弱人群中COVID-19严重结果的关键因素.
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