怀孕中的mpox ():病毒群差异及其与不同产科和胎儿结局的关联
David A Schwartz1, Phillip R Pittman2
1Perinatal Pathology Consulting, Atlanta, GA 30342, USA.
Viruses
|August 26, 2023
概括
导致最近全球疫情爆发的Mpox (麻疹) Clade IIb没有导致孕妇出现不良周产期结局. 这与早期的mopox分类 (I和IIa) 相反,这些分类与高胎儿死亡率有关.
科学领域:
- 病毒学 病毒学
- 流行病学 流行病学
- 产科 产科 产科 产科 产科
背景情况:
- 麻疹 (Mombox) 是非洲的特有病,由Clade I和Clade IIa引起,历史上与严重的围产期结局有关.
- 孕妇的I类mpox有75%的产前死亡率,包括死产和先天性mpox综合征.
- 第二类mopox也导致尼日利亚的死产.
研究的目的:
- 评估2022-2023年由Clade IIb引起的mopox疫情对孕妇和围产期结局的影响.
- 为了比较不同类型的mopox对孕产妇和胎儿健康的影响.
主要方法:
- 在2022-2023年全球疫情期间,对怀孕妇女报告的mopox病例的审查.
- 与mopox clade感染相关的围产期结果的分析.
主要成果:
- 在2022-2023年mopox疫情 (Clade IIb) 期间,至少有58名孕妇被感染.
- 对于Clade IIb感染,没有报告死亡出生或其他不良周产期结局的确诊病例.
- 与I和IIa类相比,Clade IIb mpox与较不严重的疾病有关,总体病例死亡率<0.1%.
结论:
- 负责2022-2023年爆发的mopox Clade IIb菌株与以前的菌株相比,似乎对孕妇和围产期结果产生了显著不同的影响.
- 马波克斯基层是决定妊娠和胎儿不良后果风险的关键因素.
关键词:
非洲 非洲 非洲这就是 clade clade clade 的意思.流行病学流行病学传染病 / 流行病学孕产妇健康 孕产妇健康孕产妇 - 胎儿感染的水是的水.猿病毒病毒/遗传学一个MPOX的MPOX.脊髓灰质炎病毒 脊髓灰质炎病毒麻疹病毒 (poxvirus) 是一种病毒.怀孕 怀孕 怀孕 怀孕 怀孕怀孕并发症 怀孕并发症小型天花 在天花.一个死产的死产.更多相关视频
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