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斯洛伐克几乎是没有肝炎的国家吗?

Pavol Kristian¹, Ivana Hockicková¹, Elena Hatalová²

¹Department of Infectology and Travel Medicine, Faculty of Medicine, Louis Pasteur University Hospital, Pavol Jozef Safarik University, 041 90 Kosice, Slovakia.

|August 26, 2023

概括

在斯洛伐克,D型肝炎病毒 (HDV) 感染很少见,只有不到1%的乙型肝炎表面抗原 (HBsAg) 阳性患者呈阳性. 建议对斯洛伐克所有HBsAg阳性个体进行常规的HDV检测.

科学领域:

肝病学肝病学是一种肝病学.
病毒学病毒学
公共卫生公共卫生

背景情况:

乙型肝炎病毒 (HDV) 感染影响全球4.5-13%的乙型肝炎表面抗原 (HBsAg) 阳性个体,在欧洲约为3%.
斯洛伐克HDV流行情况的数据有限或过时.

研究的目的:

评估斯洛伐克目前的高强度病毒感染率.
评估对HBsAg阳性个体进行常规HDV检测的需要.

主要方法:

分析斯洛伐克 (2005-2022) 现有的HDV数据,包括公共卫生报告和调查结果.
使用抗HDVIgG和IgM抗体和/或HDVRNA检测HDV.

主要成果:

斯洛伐克在2005年至2022年期间没有报告确诊的急性或慢性HDV感染.
一项对206名HBsAg阳性患者的前性研究发现只有一个抗HDVIgG阳性病例,没有HDVRNA.
总体而言,只有0.91% (3/329) 的HBsAg阳性患者检测出抗HDVIgG的阳性,没有人检测出HDVRNA的阳性.

结论:

斯洛伐克的HDV感染率非常低 (在HBsAg阳性患者中<1%).
由于斯洛伐克缺乏常规的HDV检测,因此需要对所有HBsAg阳性个体进行检测,符合国际建议.

关键词:

在 HDV RNA 中.抗高密度病毒抗体的抗体乙型肝炎D是一种肝炎.患病率的流行情况.

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