对于性结肠炎中大肠切除风险而言,跨壁面重度比内镜重度具有优越的预测值:一个多中心前性队列研究
Nicole Piazza O Sed1, Daniele Noviello1,2, Elisabetta Filippi2
1Gastroenterology and Endoscopy Unit, Foundation IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
通过米兰超声波标准 (MUC) 评估的跨壁活动,在性结肠炎 (UC) 患者中,比内镜严重程度更好地预测了结肠切除术. MUC独立地预测了胆管切除风险,特别是在临床活跃的疾病中.
科学领域:
- 胃肠病学 胃肠病学
- 炎症性肠道疾病研究研究
- 在IBD中进行医学成像.
背景情况:
- 内镜活动与性结肠炎 (UC) 手术风险增加相关.
- 米兰超声波标准 (MUC) >6.2有效地识别了UC中的内镜活动.
- 目前用于预测UC中胆管切除风险的方法需要改进.
研究的目的:
- 通过MUC,通过MUC来评估转移性严重程度,作为结肠切除术的优越预测因子,与UC患者内镜严重程度相比.
- 为了确定MUC是否提供了比梅奥内镜评分 (MES) 更好的胆管切除术预测准确度.
主要方法:
- 141名成人UC患者接受了盲视结肠镜和肠道超声波.
- 在随访期间评估了胆管切除术的需要.
- 后勤回归,考克斯回归和ROC分析比较了MUC和MES用于预测切除术.
主要成果:
- 两种MES (HR: 3.15) 和MUC (HR: 1.48) 都与胆管切除风险相关.
- 在多变量分析中,MUC是唯一的独立预测因素 (HR: 1.46).
- MUC的准确性 (AUROC 0.83) 比MES (AUROC 0.71) 高,是临床活跃疾病中唯一的独立预测因子.
结论:
- 通过MUC测量的外壁重度显示,与内镜重度相比,UC患者的切除风险的预测价值高于UC患者的内镜重度.
- MUC是评估UC中小肠切除风险的宝贵工具,特别是在临床活跃疾病的情况下.
更多相关视频
06:46Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
09:50Induction of Intestinal Graft-versus-host Disease and Its Mini-endoscopic Assessment in Live Mice
Published on: February 11, 2019
相关概念视频
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Drugs for Treatment of Ulcerative Colitis in IBD
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
