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Ramy Sedhom1, Rafail Beshai2, Peter Moussa3
1Division of Cardiology, Loma Linda University Medical Center, Loma Linda, CA, USA.
患有高风险肺栓塞 (PE) 和癌症的患者在医院死亡率较高. 恶性影响PE结果,特别是在转移性泌尿器,胃肠道和肺癌.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 关键护理医学 关键护理医学
背景情况:
- 高危肺栓塞 (PE) 是一种危及生命的疾病.
- 恶性病是静脉血栓塞栓症的已知危险因素,包括PE.
- 患有高风险PE和恶性瘤的患者的结局需要进一步调查.
研究的目的:
- 调查高风险肺栓塞 (PE) 患者的特征和住院结果.
- 为了比较高风险PE患者与并发性恶性瘤或没有并发性恶性瘤之间的结果.
- 确定与高风险PE患者死亡率增加相关的特定癌症类型.
主要方法:
- 全国再接收数据库 (2016-2019) 的回顾性分析.
- 确定高风险PE的住院情况.
- 与患有恶性瘤和没有恶性瘤的患者之间的住院死亡率和出血事件的比较.
主要成果:
- 在28547例高风险PE住院病例中,有16.9%出现恶性病.
- 患有恶性瘤的患者在医院调整后的住院死亡率更高 (aOR 1.91).
- 在患有恶性瘤的PE患者中,胃肠道出血更频繁,尽管其他出血类型类似.
结论:
- 恶性病是高风险PE患者医院内死亡率增加的独立预测因素.
- 转移性泌尿生殖道,胃肠道和肺癌的死亡风险最高.
- 在患有恶性瘤的患者中,使用先进的PE疗法不太常见.
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