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Updated: Jul 18, 2025

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function
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基于4-1BB的采用性T细胞治疗的第一阶段试验,针对人类端粒酶逆转录酶,在患有晚期耐火实体瘤的患者中进行

Wonyoung Choi1, Youngjoo Lee2, Beom K Choi3

  • 1Center for Clinical Trials, National Cancer Center, Goyang, Republic of Korea; Center for Rare Cancers, National Cancer Center, Goyang, Republic of Korea.

Cytotherapy
|August 26, 2023
PubMed
概括

产生人类端粒酶逆转录酶特异性CD8+T细胞 (TERTiNTs) 对癌症患者来说是可行的和安全的. 这种方法在重度预先治疗的个体中显示出疾病稳定,表明抗癌治疗的潜力.

关键词:
4-1BB受体的受体是什么?这是一种CD137抗原.有CD8阳性的T淋巴细胞.收养免疫疗法采用免疫疗法.端粒酶逆转录酶的作用

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