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克罗恩病手术的时间趋势:为期十年的单中心回顾性研究
Wei Liu1, Xiaolong Ge1, Zhaoqi Shi1
1Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
克罗恩病 (CD) 的外科干预增加,更多患者使用生物药物. 最少侵入性手术成为标准,导致CD患者的口腔瘤和并发症减少.
科学领域:
- 胃肠病学 胃肠病学
- 外科胃肠道外科手术
- 炎症性肠道疾病研究研究
背景情况:
- 克罗恩氏病 (CD) 是一种慢性炎症状况,通常需要手术干预.
- 在过去的十年中,CD的外科治疗发生了显著的进化.
研究的目的:
- 在转诊中心10年分析克罗恩病的手术趋势和结果.
- 评估患者人口统计学,治疗策略和CD的手术方法的变化.
主要方法:
- 在2013年至2022年期间,针对CD进行腹部手术的患者的前性数据收集.
- 两个不同时期的手术数据的比较:2013-2017年和2018-2022年.
- 使用曼-肯达尔趋势测试来评估时间趋势.
主要成果:
- 在研究期间,CD的外科手术容量增加.
- 观察到生物使用 (19.2%至33.5%) 和腹/囊手术 (40.0%至47.8%) 的增加.
- 腹腔镜手术增加了 (63.7%至76.5%),而急诊手术,静脉栓率 (30.5%至15.4%) 和术后并发症 (30.5%至23.0%) 减少了.
结论:
- 生物制剂的使用和透克罗恩病病例中需要手术的比例有所增加.
- 至少侵入性的手术技术现在是CD的标准实践.
- 克罗恩病的外科手术结果有了显著的改善,口腔缩和并发症率有所降低.
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