治疗风湿性肌肉骨疾病的治疗方法
W Watson Buchanan1, K D Rainsford2, Colin A Kean3
1Department of Medicine, McMaster University, Hamilton, ON, L8P 1H6, Canada.
Inflammopharmacology
|August 26, 2023
概括
发现肌肉骨疼痛管理的演变,从古老的疗法到现代的生物药物. 本概述强调了关键疗法及其改善关节健康和功能的目标.
科学领域:
- 风湿病学和整形外科
- 疼痛管理 疼痛管理
- 药理学 药理学是指药理学的学科.
背景情况:
- 长期以来,水,运动和按摩等非药物疗法一直用于肌肉骨疾病.
- 历史上的治疗方法包括选举 (mithridatium,theriaca) 和早期止痛药.
- 吗啡衍生物已经用于200多年来治疗肌肉骨疼痛.
研究的目的:
- 为提供肌肉骨疼痛管理疗法的历史概述.
- 要突出关键的药理和非药理干预措施.
- 概述管理肌肉骨疼痛的主要目标.
主要方法:
- 对历史文本和药理学发展的文献评论.
- 对肌肉骨疾病的治疗干预措施的时间分析.
- 确定关键药物类别和非医疗方法.
主要成果:
- 显著的进展包括乙撒利酸,NSAIDs,,和皮质类固醇.
- 改变疾病的抗风湿药物 (DMARDs) 从黄金化合物演变为非常成功的生物药物.
- 非药物治疗仍然与缓解症状和改善功能有关.
结论:
- 肌肉骨疼痛管理在几个世纪以来已经发展得很大.
- 治疗目标侧重于减轻疼痛,恢复功能和预防关节损伤.
- 药理学和非药理学方法的结合对于最佳的患者结果至关重要.
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