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Updated: Jul 18, 2025

Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling
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Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling

Published on: February 5, 2018

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一个全面的64个成员的IgG N-Glycan功能性甘氨酸的图书馆的分离酶组合

Wenjing Ma1,2, Zhuojia Xu1,2, Yuhan Jiang1

  • 1State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|August 26, 2023
PubMed
概括

这项研究提出了一种新的方法来合成64种免疫球蛋白G (IgG) N-甘氨酸库,有助于了解它们的免疫功能. 合成的甘将作为在生物样本中识别N-甘的标准.

关键词:
在 IgG N-甘氨酸库中.碳水化合物 碳水化合物酶催化合成的合成功能性甘油漫画是什么意思糖甘微阵列的微阵列

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Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples13:21

Chemically-blocked Antibody Microarray for Multiplexed High-throughput Profiling of Specific Protein Glycosylation in Complex Samples

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相关概念视频

Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...
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