对轻度认知障碍的老年患者的非药理干预措施进行系统审查和评估
Alternative therapies in health and medicine
|August 26, 2023
概括
包括针和炼在内的非药物干预措施,在轻度认知障碍 (MCI) 的老年人中改善认知功能是有前途的. 这些方法可以安全地提高日常生活活动和认知得分.
科学领域:
- 老年学和神经科学 在
- 综合医学是一个整体的医学.
- 基于证据的实践.
背景情况:
- 轻度认知障碍 (MCI) 影响了大量老年人群,增加了痴呆风险.
- 非药物干预为管理MCI和改善生活质量提供了潜在的途径.
- 评估这些干预措施的有效性和安全性对于临床实践至关重要.
研究的目的:
- 系统地审查和评估各种非药物干预对老年人MCI的影响.
- 综合有关针,按摩,饮食改变和运动等干预措施的证据.
- 评估现有研究的质量和证据的强度,以评估干预的有效性.
主要方法:
- 在多个数据库 (Zhichou,Wanfang,PubMed,CINAHL,Web of Science,Cochrane Library) 中从2017-2023年进行系统的文献搜索.
- 包括对老年MCI患者的药理和非药理干预的研究.
- 使用AMSTAR 2进行质量评估和通过GRADE方法进行证据分级;分析结果,如MMSE,MoCA,ADL,CDT.
主要成果:
- 评估了三个系统审查 (两个质量低,一个质量中等).
- 干预疗效的证据质量在1,2,3个月后是中等到高的;特定的认知测试显示了不同的证据水平 (MoCA高,MMSE低).
- 针显示了改善MoCA评分的潜力,报告了疼痛等不良事件.
结论:
- 非药物干预,特别是针,认知练习和体育活动,对患有MCI的老年人有潜在的益处.
- 这些干预措施可以改善认知功能和日常生活活动,同时保持有利的安全性.
- 针显示了强有力的证据,可以改善MCI患者的MoCA得分.
更多相关视频
06:58Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
Published on: January 24, 2020
7.4K
07:01Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
Published on: September 20, 2020
4.8K
相关概念视频
01:22Alzheimer's Disease: Treatment
212
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
212
01:30Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
151
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
151
01:30Cognitive Development During Adulthood
155
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
155
01:26Alzheimer's Disease: Overview
517
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
517
01:30Dementia
139
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
139