使用STEDI框架对抗微生物药物的价值评估 - 结果有多稳定?
Simon Brassel1, Amer Al Taie2, Lotte Steuten1
1Office of Health Economics, 2nd Floor Goldings House, Hay's Galleria, 2 Hay's Lane, London, SE1 2HB, UK.
Health policy (Amsterdam, Netherlands)
|August 26, 2023
概括
英国试行了一种新的医疗技术评估过程和支付模式,以解决抗菌素耐药性 (AMR). 用STEDI框架进行抗生素价值评估,强调了取决于背景的权衡和需要仔细实施的必要性.
科学领域:
- 卫生经济学 卫生经济学
- 药物经济学 药物经济学
- 公共卫生政策 公共卫生政策
背景情况:
- 抗菌素耐药性 (AMR) 构成了全球健康的重大威胁.
- 抗菌药物市场面临的挑战需要报销改革和财政激励措施.
- 现有的价值评估框架可能无法充分捕捉抗生素的多方面的价值.
研究的目的:
- 评估英格兰试点的新健康技术评估过程和抗生素支付模式.
- 评估STEDI (频谱,传播,启用,多样性,保险) 价值框架在抗生素评估中的实用性和挑战.
- 为未来的抗微生物药物价值评估策略提供信息.
主要方法:
- 从2019年开始,在英格兰实施一种新的医疗技术评估过程和支付模式.
- 应用STEDI框架,以更广泛地评估抗生素的价值.
- 分析从试点中学到的关于STEDI框架的应用和影响的经验教训.
主要成果:
- 对于抗生素价值评估,使用了STEDI框架,其中包含五个关键元素.
- 抗生素的STEDI价值概况对局部环境敏感,涉及价值元素之间的权衡.
- 决策者对整体评估结果的谨慎应用至关重要,以防止对整体评估结果的扭曲.
结论:
- STEDI框架为区分高价值和低价值抗生素产品提供了一种有价值的方法.
- 实施STEDI框架需要仔细考虑当地环境和潜在的权衡.
- 需要进一步的研究来完善STEDI评估过程并改善抗生素价值评估.
更多相关视频
09:59Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
Published on: July 21, 2023
1.3K
09:07Author Spotlight: Accelerating Diagnostic Accuracy with Direct Identification of Gram-Negatives from Blood Culture Bottles
Published on: May 24, 2024
947
相关概念视频
01:28Antimicrobial Effectiveness
44
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
44
01:29Microorganisms in Medicine and Therapeutics
53
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
53
01:30Development of Antibiotic Resistance
38
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
38
00:57Antibiotic Selection
54.7K
Overview
54.7K