饮食组成,营养物质替代和循环脂肪酸与子宫外和内脏脂肪储存相关
Michael Fridén1, Andrés Martínez Mora2, Lars Lind3
1Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden.
Clinical nutrition (Edinburgh, Scotland)
|August 26, 2023
概括
饮食脂肪类型会影响子宫外脂肪的积累. 植物性脂肪和多不和脂肪 (PUFA) 与肝脏和内脏脂肪的减少有关,与和脂肪 (SFA) 和动物脂肪不同.
科学领域:
- 营养科学 营养科学
- 代谢健康 代谢健康
- 身体组成分析 身体成分分析
背景情况:
- 之前的短期试验表明,多不和脂肪 (PUFA) 可以减少肝脏脂肪.
- 对饮食和身体脂肪分布的基于人口的研究是有限的.
- 宫外脂肪是心脏代谢疾病的危险因素.
研究的目的:
- 调查饮食,循环脂肪酸和子宫外脂肪储存之间的关联.
- 检查肝脏脂肪,内脏脂肪组织 (VAT) 和肌肉间脂肪组织 (IMAT).
- 使用能量调整模型进行可靠的分析.
主要方法:
- 英国生物库参与者的性别分层分析 (n=9,119-13,849).
- 脂肪储存的MRI,脂肪酸的NMR,饮食的24小时回忆.
- 三种能源调整模型,包括一个留出一项的方法.
主要成果:
- 在女性中,和脂肪 (SFA) 摄入量与肝脏脂肪和IMAT增加有关.
- 植物脂肪与女性的IMAT,ASAT和TAT相反相关.
- 循环PUFA与两性肝脂肪,IMAT和VAT相反相关;SFA正相关.
结论:
- 饮食脂肪类型会影响习惯饮食中的子宫外脂肪积累.
- 优先考虑植物脂肪和PUFA,而不是动物脂肪和SFA,以获得更好的代谢健康.
- 研究结果在能源调整模型中一致,并得到循环脂肪酸生物标志物的支持.
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