少是多:单剂量与延长的抗生素预防对跨关节前列腺活检
Maxwell Sandberg1, Wyatt Whitman1, Janmejay Hingu1
1Department of Urology, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, USA.
The Canadian journal of urology
|August 26, 2023
概括
对于跨 (TP) 前列腺活检,单剂量抗生素在预防感染方面与延长疗程同样有效. 这一发现支持抗生素管理,并表明更简单的预防方案可能是适当的.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 抗生素预防 抗生素预防
背景情况:
- 跨关节 (TP) 前列腺活检是诊断前列腺癌的常见程序.
- 对于TP活检的最佳抗生素预防方案仍在争论中.
- 减少活检后感染对于患者安全和抗生素管理至关重要.
研究的目的:
- 为了确定在高体积机构的TP活检后的感染率.
- 为了比较单剂量与延长抗生素预防在预防活检后感染的疗效.
主要方法:
- 在2012年至2022年期间进行的767个TP前列腺活检的回顾性审查.
- 患者被分为两组:单剂量静脉注射 (IV) 抗生素与IV抗生素以及门诊抗生素.
- 感染被定义为发烧,尿路感染症状或尿液培养在活检后72小时内呈阳性.
主要成果:
- 总体感染率很低,为1.83% (14/767).
- 单剂量组 (2.05%) 和延长疗程组 (1.53%) 的感染率相似.
- 在两种抗生素疗法之间没有观察到感染率的统计学上显著差异 (p = 0.597).
结论:
- 在TP前列腺活检后,整体感染率较低.
- 单剂量和延长抗生素预防方案在预防感染方面表现出相似的有效性.
- 这些发现支持合理使用抗生素,并要求进一步研究最佳预防策略.
相关概念视频
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
14
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
14
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
55
IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
55
Acute Pyelonephritis II: Diagnostic Studies and Management
16
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
16


