干扰或不干扰大豆和levothyroxine:这是一个问题. 一个叙事文学的文学评论
Elisa Gatta1, Virginia Maltese1, Maria Cavadini1
1Department of Clinical and Experimental Sciences, SSVD Endocrinologia, University of Brescia, Azienda Socio-Sanitaria Territoriale (ASST) Spedali Civili di Brescia, Brescia, Italy.
概括
尽管有报道称,大豆的摄入可能对levothyroxine (L-T4) 吸收的影响很小. 需要更多的研究,特别是液体L-T4配方,才能确定大豆是否会干扰甲状腺激素的吸收.
科学领域:
- 内分泌学 在内分泌学.
- 营养科学 营养科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 利沃甲状腺素 (L-T4) 是对甲状腺功能低下症的关键治疗方法.
- 豆制品是常见的饮食成分,引发了与药物的潜在相互作用的问题.
- 目前关于大豆对L-T4吸收的影响的数据有限,有时是相互矛盾的.
研究的目的:
- 系统地审查有关大豆摄入量对levothyroxine吸收的影响的现有证据.
- 根据L-T4配方 (例如,药片与液体) 来评估相互作用的潜在差异.
主要方法:
- 在PubMed/MEDLINE,Web of Science和Scopus数据库中进行全面的文献搜索.
- 包括截至2022年11月30日发表的病例报告,病例系列和原始研究.
- 审查的重点是研究大豆-L-T4相互作用的研究.
主要成果:
- 有限的数据,主要来自病例报告,表明大豆可能干扰L-T4片的吸收.
- 一项随机交叉研究发现,当与大豆异黄一起服用时,L-T4吸收没有差异.
- 关于液体L-T4配方的数据不够,尽管一项试验没有显示任何损伤.
结论:
- 豆制品对L-T4吸收的任何干扰似乎具有很小的临床意义.
- 关于大豆奶是否确切地干扰L-T4吸收的问题仍未解决.
- 需要进一步进行高质量的研究,特别是对于液体L-T4配方.
关键词:
L-T4吸收不良的情况甲氧氨酸 (Levothyroxine) 是一种含有这就是大豆大豆.豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆豆更多相关视频
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