一种非热修饰方法,以促进-酸寡糖化合物复合物的相互作用,以获得更好的封装和稳定性 - - 冷血
Junjun Zhou1, Tongliang Yang1, Ziyang Chen1
1College of Food Engineering and Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China.
International journal of biological macromolecules
|August 26, 2023
概括
冷血治疗增强了-酸寡糖化物 (zein-AOS) 纳米颗粒,以改善营养物质的输送. 这种方法提高了封装效率和稳定性,创造了先进的输送墙材料.
科学领域:
- 生物材料科学 生物材料科学
- 食品科学与技术 食品科学与技术
- 等离子体物理学的物理学
背景情况:
- 对于营养物质输送应用,正在探索zein-alginate oligosaccharide (zein-AOS) 复合物. 在营养物质输送应用方面,正在探索zein-alginate oligosaccharide (zein-AOS) 复合物.
- 了解蛋白质和糖类之间的相互作用机制对于优化复合物特性至关重要.
- 冷等离子体 (CP) 技术为材料表面修饰提供了一种新的方法.
研究的目的:
- 为了研究冷血 (CP) 促进蛋白质-糖相互作用的机制,在 zein-AOS 复合物中.
- 优化CP处理条件,以增强AOS纳米粒子 (NP) 性能.
- 为了评估CP-修改的 zein-AOS NP作为营养物质的输送壁材料的性能.
主要方法:
- Zein-AOS纳米颗粒 (NP) 使用抗溶剂方法进行制备.
- 在不同的条件下 (例如,85W2分钟) 接受了Zain-AOS溶液的冷血 (CP) 处理.
- 对NP的表征包括粒子大小,特定表面积,表面电荷和稳定性评估. 黄素被用作封装研究的模型营养素.
主要成果:
- CP处理显著改善了Zeen和AOS之间的键和静电相互作用.
- 在最佳条件下 (zein-AOS85),CP-修改的ain-AOSNP表现出更小的粒子尺寸 (234.67nm),更大的特定表面积 (9.443 m2/g) 和更高的表面电荷 (-35.43 mV).
- 在CP治疗后,黄素的封装效率 (EE) 从63.80%增加到85.17%,通过改善的相互作用证明了营养结合的增强.
- 由此产生的输送系统在各种pH值,离子强度,储存和分散条件下表现出极好的稳定性.
结论:
- 冷血治疗是修改ain-AOS复合物的有效方法,增强蛋白质-糖相互作用.
- 经过CP处理的ain-AOSNP显示出作为传递壁材料的优越特性,提供更好的稳定性和营养包装.
- 改进的CP-修改的Zeen-AOSNP的增强相互作用和稳定性为先进的营养递送系统提供了重大潜力.
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