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欧洲的乙型肝炎和C型肝炎:来自2019年全球疾病负担研究的更新

The Lancet. Public health

|August 26, 2023

概括

病毒性乙型肝炎和型肝炎仍然是欧洲的重大健康负担,尽管2010-2019年期间疾病发病率有所下降. 为了在2030年前消除乙型肝炎病毒 (HBV) 和乙型肝炎病毒 (HCV),密集干预至关重要.

科学领域:

流行病学流行病学
公共卫生公共卫生
病毒学病毒学

背景情况:

到2030年消除病毒性肝炎是一个全球卫生优先事项.
乙型肝炎病毒 (HBV) 和型肝炎病毒 (HCV) 在欧洲面临重大健康挑战.
了解疾病负担趋势对于有针对性的干预措施至关重要.

研究的目的:

评估2010年至2019年欧洲的HBV和HCV负担.
分析疾病发病率,流行率,死亡率和DALYs的时间变化.
为实现病毒性肝炎消除目标的战略提供信息.

主要方法:

使用的疾病,伤害和风险因素研究 (GBD) 2019年的全球负担估计.
分析了HBV和HCV相关的急性肝炎,肝硬化和肝癌的数据.
报告了关键指标的年龄标准化利率和百分比变化.

主要成果:

观察到急性乙型肝炎和HBV相关肝硬化病的年龄标准化发病率和死亡率的下降.
型肝炎的发病率和死亡率也下降了,尽管与HCV相关的肝癌在病例和DALY中呈现了增加的趋势.
在急性乙型肝炎和乙型肝炎相关肝硬化和急性乙型肝炎和乙型肝炎相关肝硬化中,DALYs显著降低.

结论:

尽管取得了进展,但HBV和HCV仍然是欧洲的高疾病负担.
为了实现2030年消除目标,需要协调和加强干预.
进一步的研究和公共卫生工作对于消除乙型肝炎和C型肝炎至关重要.

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