在接受膜膜状细胞癌治愈治疗的患者中,复发的模式
Saadia Farooq1, Farhan Zubair2, Jeremy McMahon1
1Oral and Maxillofacial Surgery Department, Queen Elizabeth Hospital, 1345 Govan Road, Glasgow G51 4TF, UK.
The British journal of oral & maxillofacial surgery
|August 26, 2023
概括
外节延伸 (ENE) 和节点转移是大膜状细胞癌 (MASCC) 区域复发的关键预测因素. 这一发现对于了解MASCC患者的复发模式和指导部治疗策略至关重要.
科学领域:
- 在瘤学瘤学.
- 头部和部手术 头部和部手术
- 病理学 病理学 病理学
背景情况:
- maksillary alveolus状细胞癌 (MASCC) 在治疗和复发方面提出了独特的挑战.
- 了解复发模式对于改善患者的治疗结果和定制治疗策略至关重要.
研究的目的:
- 调查治疗MASCC的患者复发的模式.
- 确定预测不同类型复发的临床病理变量,重点关注区域复发.
主要方法:
- 从41名接受治疗切除的MASCC患者的临床病理学数据的回顾性分析.
- 使用单变量和多变量回归分析来确定复发的预测因素.
主要成果:
- 在41名患者中,有10名患者出现区域性复发.
- 节点转移,特别是在节点外瘤扩散 (ENE) 时,与区域性复发有显著的相关性.
- 多变量分析证实NEE是区域复发的独立预测因素.
结论:
- 节点疾病和ENE是MASCC区域复发的重要预测因素.
- 节点疾病和ENE的存在预示着对侧区域的复发,需要仔细的部管理.
- 由于复发风险,涉及 palatal 方面的 MASCC 应该被管理,将其视为中线疾病.
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