使用2022年ESPEN和EASO共识声明标准的sarcopenic肥胖症 - 来自德国KORA-Age研究的结果
Sabine Schluessel1, Marie-Theres Huemer2, Annette Peters3
1Department of Medicine IV, University Hospital, Ludwig Maximilian University Munich, Ziemssenstraße 5, 80336 Munich, Germany.
Obesity research & clinical practice
|August 26, 2023
概括
肥胖症 (sarcopenic obesity) 影响了4.5%的德国老年人,与残疾和其他健康问题有关. 这项研究将新的诊断标准应用于基于人口的样本.
科学领域:
- 老年学是一门学科.
- 肥胖问题研究研究
- 代谢健康 代谢健康
背景情况:
- 欧洲临床营养和新陈代谢学会 (ESPEN) 和欧洲肥胖研究协会 (EASO) 最近更新了对形肥胖的标准.
- 使用这些新标准来评估sarcopenic肥胖的流行率和临床相关性,对于了解其对老龄化人口的影响至关重要.
研究的目的:
- 通过2022年ESPEN和EASO标准确定德国老年人群中肥胖症的流行率.
- 调查sarcopenic肥胖症与各种临床特征之间的关联,包括体力活动,残疾,多病症和多药性.
主要方法:
- 利用来自德国南部的KORA-Age研究的998名参与者 (65岁以上) 的数据.
- 定义的sarcopenic肥胖症基于手握强度降低,骨肌肉质量指数降低和脂肪质量增加,通过生物电阻分析测量.
- 采用后勤回归来分析sarcopenic肥胖和临床因素之间的关联,调整人口统计学变量.
主要成果:
- 肥胖症的发病率为4.5% (男性为5.0%,女性为4.0%).
- 在调整后,sarcopenic肥胖与残疾 (OR 2.87),多病症 (OR 2.59),多药性 (OR 1.96),认知障碍 (OR 3.03) 和关节炎 (OR 2.66) 有显著关联.
结论:
- 肥胖症是德国老年人中普遍存在的疾病.
- 这种情况与较高的残疾负担,多病症和其他不良临床特征有关,突出其临床意义.
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