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Updated: Jul 18, 2025

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在DmDcr-2寡合体上R2D2和Loqs-PD协同调节的结构机制

Ting Deng1, Shichen Su1, Xun Yuan2

  • 1State Key Laboratory of Genetic Engineering, Collaborative Innovation Centre of Genetics and Development, Department of Biochemistry and Biophysics, Institute of Plant Biology, School of Life Sciences, Fudan University, 200438, Shanghai, China.

Nature communications
|August 26, 2023
PubMed
概括

小干扰RNAs (siRNAs) 对RNA干扰至关重要. 新的冷EM结构揭示了R2D2和Loqs-PD共因子如何同时结合Dicer-2 (DmDcr-2),形成siRNA处理所必需的纤维.

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