ABCD2评分对前循环TIA和后循环TIA具有相当的中风风险预测
Shuang Cao1, Lu Zhao1, Lulu Pei1
1Department of Neurology, The First Affiliated Hospital of Zhengzhou University, No. 1 East Jianshe Road, Zhengzhou, 450052, Henan Province, People's Republic of China.
Scientific reports
|August 26, 2023
概括
该ABCD2得分有效预测短期中风风险在过渡性缺血性心脏病发作 (TIA) 患者心脏病发作在前后循环区域. 这一分数表明TIA两组的预测能力相似.
科学领域:
- 神经学 神经学
- 神经成像是一种神经成像.
- 脑卒中医学 脑卒中医学
背景情况:
- 过渡性缺血性攻击 (TIA) 在临床上被分为前部循环 (AC) 和后部循环 (PC) 事件.
- 在AC-TIA之后,ABCD2评分被确立为预测中风风险,但其在PC-TIA中的有效性仍在争论中.
- 神经成像可以根据心脏病发作位置区分TIA,从而潜在地完善风险评估.
研究的目的:
- 根据心脏病发作的神经成像结果对TIA患者进行分类.
- 在AC-TIA和PC-TIA中评估ABCD2评分对复发性中风风险的预测值.
- 为了比较前后循环TIA之间的ABCD2得分的预测性能.
主要方法:
- 来自州大学第一附属医院的TIA数据库的回顾性分析.
- 患有过渡性心脏病发作 (TSI) 症状的患者根据扩散权重成像的心脏病发作位置分为AC-TSI和PC-TSI组.
- 在7天和90天内重复性中风是主要结果,使用接收器操作员特征 (ROC) 曲线分析评估ABCD2得分预测能力.
主要成果:
- 这项研究包括382名AC-TSI和112名PC-TSI患者.
- 复发性中风的发生率为AC-TSI的9.9% (7天) 和17.3% (90天),PC-TSI的9.8% (7天) 和17.0% (90天).
- 在ABCD2得分的ROC曲线下的面积 (AUC) 为AC-TSI的0.637和PC-TSI的0.683,在7天内,两组之间没有统计学上显著的差异 (P=0.62). 在90天后观察到类似的结果.
结论:
- 在AC-TSI和PC-TSI患者中,ABCD2得分显示了对短期复发性中风风险的预测能力.
- 该ABCD2得分的预测性能在前后循环TIA与心脏病发作之间是可比的.
- 基于神经成像的TIA分类有助于评估不同血管区域的风险预测得分的有用性.
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