一种稳定的核心外金属有机框架@共价有机框架复合物作为固相提取吸收剂,用于选择性丰富和确定黄类
Mingcai Ma1, Xiaofeng Lu2, Licheng Wang2
1CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Journal of chromatography. A
|August 27, 2023
概括
一种新的核心外金属有机框架@共价有机框架 (MOF@COF) 复合物增强了疏水性和稳定性,用于高效的疏水性黄的固相提取 (SPE). 这种吸附剂在复杂样品中显示出高提取效率和灵敏度.
科学领域:
- 材料科学:开发先进的复合材料用于分离科学.
- 分析化学:新型吸附剂在固相提取中的应用.
- 纳米技术:核心外MOF@COF结构的合成和表征.
背景情况:
- 疏水性和稳定性是提取应用中的金属有机框架 (MOF) 的关键限制.
- 现有的吸附剂可能缺乏有效提取疏水化合物的必要性质.
- 复合材料的开发可以克服单个组件的局限性.
研究的目的:
- 合成一个稳定的核心外MOF@COF复合物,用于增强固相提取 (SPE).
- 为了改善水友性MOF的疏水性和稳定性,用于实际应用.
- 开发一种敏感的分析方法,用于提取疏水性黄素.
主要方法:
- 通过希夫基反应制备一个核心外NH2-MIL-101(Fe) @TAPB-FPBA-COF复合物.
- MOF@COF复合物的应用在疏水性黄类的固体相提取 (SPE) 中.
- 优化SPE条件与具有紫外线可见检测 (HPLC-UV) 的高性能液体染色学相结合.
主要成果:
- 与单个组件相比,MOF@COF复合材料具有显著改善的疏水性和稳定性.
- 开发的SPE方法表现出极好的线性 (R2 ≥0.9967),低检测极限 (0.02-0.08 ng mL-1),以及良好的可重复性.
- MOF@COF吸附剂在葡萄汁和蜂蜜等复杂矩阵中显示出高提取效率的黄类,回收率在84.5%至104.6%之间.
结论:
- 合成的稳定MOF@COF核心外复合物是一种有前途的吸附剂,用于疏水化合物的SPE.
- 疏水性COF外有效地屏蔽了疏水性MOF核心,提高了其性能.
- 开发的分析方法是敏感的,有选择性的,适用于分析现实世界食品样本中的黄类.
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