在结肠癌中免疫调节BTN2A1,BTN2A2和BTNL3基因的框架转移突变

Jae Woong Kim1, Doeun Rim1, Chang Hyeok Ann2

  • 1Department of Pathology, College of Medicine, The Catholic University of Korea, Seoul 06591, the Republic of Korea.

PubMed
概括

布蒂罗菲林基因 (BTN2A1,BTN2A2,BTNL3) 在结肠癌中显示突变和表达变化,特别是在微卫星不稳定性高的瘤中. 这些变化表明,通过影响免疫反应,在结肠癌的发展中发挥了作用.

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