相关实验视频
Updated: Jul 18, 2025

05:51
A Neuronal Apoptosis Model induced by Spinal Cord Compression in Rat
Published on: June 29, 2021
1.4K
在患有退行性宫髓病的患者中,大脑干和皮下区域的体积损失及其与脊髓压缩严重程度的关联
Elena Filimonova1, Ivan Vasilenko2, Yulij Kubetsky2
1Federal Center of Neurosurgery Novosibirsk, Nemirovich-Danchenko Str. 132/1, Novosibirsk 630087, Russia; Novosibirsk State Medical University, Krasny Prospect St. 52, Novosibirsk 630091, Russia.
Clinical neurology and neurosurgery
|August 27, 2023
概括
在患有退行性宫骨髓病 (DCM) 的患者中,大脑干中大脑体积的损失是明显的. 这种脑干结构的减少与DCM患者的脊髓压缩严重程度相关.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 放射学 放射学是一门学科.
背景情况:
- 退行性宫髓病 (DCM) 与大脑的结构和功能变化有关.
- 之前的研究表明,DCM患者的大脑干结构连接的改变.
- 这项研究调查了DCM中基底,乳头和脑干结构的体积损失.
研究的目的:
- 为了确定DCM患者是否发生特定大脑结构的体积损失.
- 评估大脑结构体积与DCM中脊髓压缩严重程度之间的关联.
主要方法:
- 对大脑和脊髓的磁共振成像 (MRI) 对47名DCM患者和25名宫激素病控制进行了测试.
- 使用FreeSurfer量化了大脑干,基底和thalamic体积.
- 脊髓MRI数据分析了横截面积 (CSA) 和分数异构 (FA),并评估了与大脑形态学的相关性.
主要成果:
- 与对照人群相比,DCM患者的整个脑干,长髓,pons和中脑体积显著减少.
- 在DCM患者中观察到左门体积减少的趋势.
- 长髓体积损失与脊髓压缩严重程度和白质损伤有显著的相关性.
结论:
- 患有退行性宫髓病的患者表现出大脑干结构体积减少.
- 这些观察到的大脑体积变化与DCM中脊髓压缩的严重程度有关.
相关概念视频
Spinal Cord: Gross Anatomy
3.3K
The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
3.3K
Spinal Cord: Cross-sectional Anatomy
2.0K
The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
Gray Matter and its Components
Central to the gray matter is...
2.0K
Brainstem
2.2K
The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
2.2K

