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周围血液参数的预后值在所有频率的突发感应神经神经听力损失上
Hongcun Sun1, Wenbo Jiang1, Jian Wang1
1The Affiliated People's Hospital of Ningbo University, Department of Otorhinolaryngology-Head and Neck Surgery, Ningbo, China.
Brazilian journal of otorhinolaryngology
|August 27, 2023
概括
纤维素水平,而不是C-反应蛋白,可以预测突然感觉神经听力损失 (SSNHL) 的结果. 纤维素素的早期监测对于管理SSNHL预后至关重要.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 血液学 血液学 血液学
- 内部医学 内部医学
背景情况:
- 突发感神经听力损失 (SSNHL) 是一种严重的疾病,需要有效的预后指标.
- 外周血液参数越来越多地被调查,因为它们在预测各种医疗结果中的作用.
研究的目的:
- 评估外周血液参数的预测值,以预测所有频率的SSNHL.
- 确定可以指导SSNHL治疗策略的关键生物标志物.
主要方法:
- 分析了78名患有所有频率SSNHL的患者队列.
- 患者被分为有效和无效治疗组.
- 用物流回归和接收器运行特征 (ROC) 曲线分析来评估预后变量.
主要成果:
- 对于SSNHL的整体有效率为61.5%.
- 在有效治疗组中观察到治疗前听力水平较低,糖尿病患病率降低.
- 纤维素素水平升高与预后差显著相关,在ROC分析中具有85.4%的灵敏度和60.0%的特异性.
结论:
- 纤维素水平是所有频率SSNHL的预后的一个有价值的预测指标.
- C-反应蛋白水平没有显示出显著的预后影响.
- 建议在SSNHL急性阶段监测纤维素水平,以改善患者管理.
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