不同的弱点切断点对美国老年人未来认知障碍的作用
Ryan McGrath1, Grant R Tomkinson2, Jeremy M Hamm3
1Healthy Aging North Dakota (HAND), North Dakota State University, Fargo, ND, USA; Department of Health, Nutrition, and Exercise Sciences, North Dakota State University, Fargo, ND, USA; Fargo VA Healthcare System, Fargo, ND, USA; Department of Geriatrics, University of North Dakota, Grand Forks, ND, USA; Alliance for Research in Exercise, Nutrition, and Activity (ARENA), Allied Health & Human Performance, University of South Australia, Adelaide, South Australia, Australia.
Journal of the American Medical Directors Association
|August 27, 2023
概括
绝对握力强度的弱点预测了老年人的认知能力下降. 结合多种弱点测量方法可以提高对未来认知障碍的预测.
科学领域:
- 老年学是一门学科.
- 认知神经科学 认知神经科学
- 公共卫生 公共卫生
背景情况:
- 手握强度 (HGS) 是老年人整体健康的关键指标.
- 现有的HGS弱点切断点可能无法一致预测认知表现.
- 不同的HGS弱点定义的预后价值需要进一步调查.
研究的目的:
- 评估HGS绝对和正常化弱点和未来认知障碍之间的关联.
- 检查认知衰退的综合弱点标准的预测效用.
- 确定最有效的HGS措施来预测美国老年人的认知障碍.
主要方法:
- 来自健康和退休研究 (2006-2018) 的11,116名65岁以上的成年人纵向小组的分析.
- 使用修改的认知状态的电话采访来评估认知功能.
- 用绝对,身体质量正常化和身体质量指数正常化切割点来定义手握强度 (HGS) 的弱点.
主要成果:
- 根据绝对HGS截止点定义的弱点与未来认知障碍的几率显著增加有关 (OR 1.62).
- 规范化的HGS切割点 (体重和BMI) 没有显示与认知障碍的显著关联.
- 满足所有三个弱点标准的个体,认知障碍的几率增加了 (OR为1.47),而满足一个或两个标准并没有产生显著的结果.
结论:
- 不同的手握强度弱点切断点对认知障碍具有不同的预后值.
- 聚合多个弱点标准可能会提高认知衰退的预测准确性.
- 弱点类别与认知功能之间的特定关联需要进一步考虑.
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