在八重生人中左心室尾封闭后的结果和再录取:当代分析
Kirolos Barsoum1, Mahmoud Khalil2, Mohamed Magdi Eid3
1University of Texas Medical Branch, Galveston, TX, USA.
Journal of the American Medical Directors Association
|August 27, 2023
概括
八十岁的左心房附属体封闭 (LAAO) 显示初始再入院率较低,但胃肠道出血增加. 对这个老年人群来说,仔细的抗血栓管理至关重要.
科学领域:
- 心脏病学 心脏病学
- 医疗器械 医疗器械
- 老年医学 老年医学
背景情况:
- 在临床试验中,对于左心室尾阻塞 (LAAO) 的临床试验中,八胞胎人数不足.
- 了解这个老年人群的再接收原因和结果对于临床实践至关重要.
研究的目的:
- 检查80岁及以上患者在LAAO后再入院的原因和结果.
- 为了比较LAAO和抗凝血 (AC) 之间的再接收率和原因.
主要方法:
- 使用国家再接收数据库 (2016-2018) 进行回顾性队列研究.
- 确定80岁以上的心房动或LAAO患者,不包括那些在索引入院期间死亡的患者.
- 使用ICD-10-CM代码和统计分析 (Stata v17) 包括回归分析来比较结果.
主要成果:
- 在491,329名AC和2030名LAAO患者中,LAAO组在45天 (P < .01) 的所有原因再接收率都较低.
- 胃肠道出血 (GIB) 在LAAO组在45,90和180天 (P < .01) 增加了再入院,但整体GIB率在各组之间相似.
- 在LAAO和AC组之间没有观察到中风或内出血率的显著差异.
结论:
- 八十岁的LAAO与GIB在6个月内初始增加有关,尽管长期与AC没有显著差异.
- 抗血栓策略需要仔细考虑LAAO后,以减轻这个脆弱的老年人群的出血风险.
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