前部部分的渐进变化及其对前腔室角度的影响,主要角度关闭疾病
Jiehoon Kwak1, Kilhwan Shon2, Yunhan Lee1
1From the Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center (J.K., Y.L., K.R.S.), Seoul.
American journal of ophthalmology
|August 27, 2023
概括
在接受激光外周 iridotomy (LPI) 治疗的初级角度闭合疾病 (PACD) 患者中,老化增加了透镜,缩小了前腔角. 然而,与年龄相关的瞳孔收缩可能会抵消这种收窄效应.
科学领域:
- 眼科医生 眼科 眼科
- 前段成像前段成像的使用
- 玻璃眼研究研究 玻璃眼研究
背景情况:
- 主要角关闭疾病 (PACD) 由于前腔角狭窄,对视力构成风险.
- 激光外周 iridotomy (LPI) 是一个常见的治疗方法,以改善水性幽默的流动和扩大角度.
- 在LPI后前段的纵向变化尚未完全理解.
研究的目的:
- 用串行OCT成像分析前段参数的纵向变化.
- 确定这些变化对LPI后PACD眼睛前腔角 (ACA) 的影响.
主要方法:
- 对103名接受LPI的PACD患者进行了回顾性队列研究.
- 在6.5年的时间里,AS-OCT考试的平均值为6.7次.
- 多变量线性混合效应模型 (LMEMs) 分析了ACD,AOD750,ARA750,IT750,LV和PD的时间变化.
主要成果:
- 透镜 (LV) 随着时间的推移显著增加 (11.6μm/y),与角度参数负相关.
- 角度隙面积 (ARA750) 显著减少 (-2.3 × 103 μm2/年).
- 瞳孔直径 (PD) 随着年龄的增长而减少 (-13.7μm/y),虹膜厚度的边缘变薄 (IT750).
结论:
- 随着年龄的增长,透镜的增加有助于前腔的浅化和LPI后PACD眼睛的ACA缩小.
- 与年龄相关的瞳孔收缩和外围虹膜变薄可能部分抵消ACA收窄.
- 纵向AS-OCT监测对于了解PACD的疾病进展和治疗效果至关重要.
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