紫外线C介导的Candida auris的失活,这是一个迅速出现的健康威胁
Carolina Koutras1, Richard L Wade1
1Department of Clinical Research, R-Zero Systems, Salt Lake City, UT.
American journal of infection control
|August 27, 2023
概括
紫外线C (UV-C) 光有效地使Candida auris,一种危险的多药耐药生物体 (MDRO) 在表面上失活. 这项研究表明,紫外线是预防医疗相关感染和提高患者安全的有希望的工具.
科学领域:
- 感染控制 感染控制
- 微生物学 微生物学
- 环境卫生环境卫生
背景情况:
- 医疗相关感染 (HAI) 是一个主要的患者安全问题,特别是那些由多药耐药生物体 (MDROs) 引起的.
- 黄 (C. auris) 是一种新兴的MDRO真菌,由于高死亡率和控制方面的挑战,被确定为迫切威胁.
- 有效的消毒策略对于防止C. auris在医疗机构的传播至关重要.
研究的目的:
- 为了评估254nm紫外线C (UV-C) 光在硬表面不活性化C. auris的有效性.
- 用UV-C消毒来确定显著减少C. auris所需的时间.
- 评估紫外线光作为对MDROs的辅助感染控制措施的潜力.
主要方法:
- 使用了带有高性能灯泡的移动UV-C消毒塔.
- 实验是在一个患者房间大小的试验室中进行的.
- 在UV-C暴露后,测量了C. auris在硬表面的失活率.
主要成果:
- 紫外线-C光实现了≥99.97% (≥3.86 log10) 的C. auris.无活化.
- 这种高水平的无活化是在连续暴露7分钟内实现的.
- 该研究在模拟的临床环境中显示出显著的疗效.
结论:
- 254nm紫外线光对在硬表面上的C. auris无活化非常有效.
- 紫外线消毒可以作为补充措施来打击由C. auris和其他MDROs引起的HAI.
- 采用UV-C消毒协议可以提高患者的安全性,并减轻MDRO在医疗机构的威胁.
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