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盆腔外阴的患病率和压力变化在Cloacal Exstrophy (Ophalocele-Exstrophy-Imperforate Anus-Spinal Defects Syndrome) 关闭期间

Ted Lee¹, Elizabeth Roth², Aseem Shukla³

¹Boston Children's Hospital, Department of Urology, Boston, MA.

|August 27, 2023

概括

盆腔外皮 (PEK) 在30%的患有腹-外-孔门脊椎缺陷综合征 (OEIS) 的患者中被发现. 在手术修复过程中,脏参数显示PEK的变化较高,相比于脏在手术修复过程中.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
儿科手术儿科手术
医疗成像医学成像

背景情况:

盆腔外 (PEK) 是一种先天性异常,脏位于盆腔内.
脊缺陷综合征 (OEIS) 是一种复杂的疾病,可能包括PEK.
OEIS的手术修复,特别是骨近似,可能会影响脏参数.

研究的目的:

确定OEIS患者中PEK的流行率.
为了比较脏参数,包括脏骨盆压力 (RPP),最大抽缩速度 (PSV) 和阻力指数 (RI),在骨近似测试后,PEK和正义脏之间.
评估这些变化对外科手术期间管理的影响.

主要方法:

对80名OEIS患者进行了回顾性审查,以确定PEK的流行率.
在四名OEIS患者中,既有PEK和正脏,RPP,PSV和RI在第二阶段修复期间在阴骨近似前后测量.
配对的t测试用于对参数进行统计分析.

主要成果:

在OEIS患者中,PEK的患病率为30% (80人中24人),其中4%患有单次PEK.
在骨近似后,PEK (+26.0 mmHg) 中RPP的平均增加高于与正位脏 (+10.3 mmHg) 相比.
在PSV和RI的平均变化也显示了PEK和正脏之间的明显模式,尽管在统计学上并不显著 (P=0.09和P=0.29,分别).

结论:

盆腔外阴在OEIS患者中很常见.
像RPP,PSV和RI这样的脏参数在手术修复期间在PEK表现出更大的变化,而不是在正确脏.
实时RPP监测可能有利于在术后期管理OEIS患者,特别是那些孤独PEK患者.

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